| Host: | Rabbit |
| Applications: | WB/IF/ELISA |
| Reactivity: | Human/Mouse |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description : | Rabbit polyclonal antibody anti-Forkhead box protein H1 (10-59 aa) is suitable for use in Western Blot, Immunofluorescence and ELISA research applications. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: | 1 mg/mL |
| Dilution Range: | WB 1:500-1:2000 IF 1:200-1:1000 ELISA 1:10000 |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FOXH1 |
| Gene ID: | 8928 |
| Uniprot ID: | FOXH1_HUMAN |
| Immunogen Region: | 10-59 aa |
| Specificity: | FAST-1/2 Polyclonal Antibody detects endogenous levels of FAST-1/2 protein. |
| Immunogen: | The antiserum was produced against synthesized peptide derived from the human FOXH1 at the amino acid range 10-59 |
| Function | Transcriptional activator. Recognizes and binds to the DNA sequence 5'-TGTGTGTATT-3'. Required for induction of the goosecoid (GSC) promoter by TGF-beta or activin signaling. Forms a transcriptionally active complex containing FOXH1/SMAD2/SMAD4 on a site on the GSC promoter called TARE (TGF-beta/activin response element). |
| Protein Name | Forkhead Box Protein H1 Forkhead Activin Signal Transducer 1 Fast-1 Hfast-1 Forkhead Activin Signal Transducer 2 Fast-2 |
| Database Links | Reactome: R-HSA-1181150 Reactome: R-HSA-1502540 Reactome: R-HSA-9754189 Reactome: R-HSA-9796292 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Forkhead Box Protein H1 antibody Anti-Forkhead Activin Signal Transducer 1 antibody Anti-Fast-1 antibody Anti-Hfast-1 antibody Anti-Forkhead Activin Signal Transducer 2 antibody Anti-Fast-2 antibody Anti-FOXH1 antibody Anti-FAST1 antibody Anti-FAST2 antibody |
Information sourced from Uniprot.org