Anti-FOLH1/PSMA antibody (Lys44-Ala750) [1A097] (STJA0022002)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationUnconjugated
IsotypeIgG1
ImmunogenMammalian cells-derived recombinant Human FOLH1/PSMA (Lys44-Ala750)
General Information
| Short Description | Mouse monoclonal Glutamate Carboxypeptidase 2 (Lys44-Ala750) antibody for use in ELISA, IHC and WB in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/IHC/WB |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO) MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS |
Product Properties
| Clonality | Monoclonal |
| Clone ID | 1A097 |
| Isotype | IgG1 |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Protein A/G purified from cell culture supernatant |
| Formulation | 0.01M PBS, pH 7.4. |
| Storage Instruction | Suitable for storage at +4°C between 1-2 weeks For longer term store at-20°C for up to 12 months |
Target Information
| Gene Symbol | FOLH1 |
| Gene ID | 2346 |
| Uniprot ID | FOLH1_HUMAN |
| Immunogen | Mammalian cells-derived recombinant Human FOLH1/PSMA (Lys44-Ala750) |
| Immunogen Region | Lys44-Ala750 |
Additional Info
| Post Translational Modifications | The first two amino acids at the N-terminus of isoform PSMA' appear to be cleaved by limited proteolysis. The N-terminus is blocked. |
| Function | Has both folate hydrolase and N-acetylated-alpha-linked-acidic dipeptidase (NAALADase) activity. Has a preference for tri-alpha-glutamate peptides. In the intestine, required for the uptake of folate. In the brain, modulates excitatory neurotransmission through the hydrolysis of the neuropeptide, N-aceylaspartylglutamate (NAAG), thereby releasing glutamate. Involved in prostate tumor progression. Also exhibits a dipeptidyl-peptidase IV type activity. In vitro, cleaves Gly-Pro-AMC. |
| Protein Name | Glutamate Carboxypeptidase 2Cell Growth-Inhibiting Gene 27 ProteinFolate Hydrolase 1Folylpoly-Gamma-Glutamate CarboxypeptidaseFgcpGlutamate Carboxypeptidase IiGcpiiMembrane Glutamate CarboxypeptidaseMgcpN-Acetylated-Alpha-Linked Acidic Dipeptidase INaaladase IProstate-Specific Membrane AntigenPsmPsmaPteroylpoly-Gamma-Glutamate Carboxypeptidase |
| Database Links | Reactome: R-HSA-8963693 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Ii Membrane ProteinIsoform Psma': Cytoplasm |
| Alternative Antibody Names | Anti-Glutamate Carboxypeptidase 2 antibodyAnti-Cell Growth-Inhibiting Gene 27 Protein antibodyAnti-Folate Hydrolase 1 antibodyAnti-Folylpoly-Gamma-Glutamate Carboxypeptidase antibodyAnti-Fgcp antibodyAnti-Glutamate Carboxypeptidase Ii antibodyAnti-Gcpii antibodyAnti-Membrane Glutamate Carboxypeptidase antibodyAnti-Mgcp antibodyAnti-N-Acetylated-Alpha-Linked Acidic Dipeptidase I antibodyAnti-Naaladase I antibodyAnti-Prostate-Specific Membrane Antigen antibodyAnti-Psm antibodyAnti-Psma antibodyAnti-Pteroylpoly-Gamma-Glutamate Carboxypeptidase antibodyAnti-FOLH1 antibodyAnti-FOLH antibodyAnti-NAALAD1 antibodyAnti-PSM antibodyAnti-PSMA antibodyAnti-GIG27 antibody |
Information sourced from Uniprot.org