| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Fibronectin type III domain-containing protein 4 (33-83) is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:1000-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
FNDC4 |
| Gene ID: |
64838 |
| Uniprot ID: |
FNDC4_HUMAN |
| Immunogen Region: |
33-83 |
| Specificity: |
This antibody detects endogenous levels of human FNDC4 |
| Immunogen: |
Synthesized peptide derived from human FNDC4 AA range: 33-83 |
| Function | Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to down-regulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by down-regulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis. |
| Protein Name | Fibronectin Type Iii Domain-Containing Protein 4Fibronectin Type Iii Repeat-Containing Protein 1 |
| Cellular Localisation | MembraneSingle-Pass Type I Membrane ProteinSecretedThe N-Terminus Is Probably Cleaved To Release A Secreted Extracellular Portion Of The Protein |
| Alternative Antibody Names | Anti-Fibronectin Type Iii Domain-Containing Protein 4 antibodyAnti-Fibronectin Type Iii Repeat-Containing Protein 1 antibodyAnti-FNDC4 antibodyAnti-FRCP1 antibodyAnti-UNQ6389 antibodyAnti-PRO21134 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
