Anti-FN3K antibody (130-210 aa) (STJ191809)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human protein at the amino acid range 130-210
General Information
| Short Description | Rabbit polyclonal anti-Fructosamine-3-kinase (130-210 aa) for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FN3K |
| Gene ID | 64122 |
| Uniprot ID | FN3K_HUMAN |
| Immunogen | Synthesized peptide derived from the human protein at the amino acid range 130-210 |
| Immunogen Region | 130-210 aa |
| Specificity | FN3K Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Fructosamine-3-kinase involved in protein deglycation by mediating phosphorylation of fructoselysine residues on glycated proteins, to generate fructoselysine-3 phosphate. Fructoselysine-3 phosphate adducts are unstable and decompose under physiological conditions. Involved in intracellular deglycation in erythrocytes. Involved in the response to oxidative stress by mediating deglycation of NFE2L2/NRF2, glycation impairing NFE2L2/NRF2 function. Also able to phosphorylate psicosamines and ribulosamines. |
| Protein Name | Fructosamine-3-KinaseProtein-Psicosamine 3-Kinase Fn3kProtein-Ribulosamine 3-Kinase Fn3k |
| Database Links | Reactome: R-HSA-163841 |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Fructosamine-3-Kinase antibodyAnti-Protein-Psicosamine 3-Kinase Fn3k antibodyAnti-Protein-Ribulosamine 3-Kinase Fn3k antibodyAnti-FN3K antibody |
Information sourced from Uniprot.org