Anti-FMO5 antibody (STJA0007524)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FMO5
General Information
| Short Description | Rabbit polyclonal anti-Flavin-containing monooxygenase 5 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FMO5 |
| Gene ID | 2330 |
| Uniprot ID | FMO5_HUMAN |
| Immunogen | Synthesized peptide derived from human FMO5 |
| Specificity | This antibody detects endogenous levels of FMO5 at Human, Mouse, Rat |
Additional Info
| Function | Acts as a Baeyer-Villiger monooxygenase on a broad range of substrates. Catalyzes the insertion of an oxygen atom into a carbon-carbon bond adjacent to a carbonyl, which converts ketones to esters. Active on diverse carbonyl compounds, whereas soft nucleophiles are mostly non- or poorly reactive. In contrast with other forms of FMO it is non- or poorly active on 'classical' substrates such as drugs, pesticides, and dietary components containing soft nucleophilic heteroatoms (Probable). Able to oxidize drug molecules bearing a carbonyl group on an aliphatic chain, such as nabumetone and pentoxifylline. Also, in the absence of substrates, shows slow but yet significant NADPH oxidase activity. Acts as a positive modulator of cholesterol biosynthesis as well as glucose homeostasis, promoting metabolic aging via pleiotropic effects. |
| Protein Name | Flavin-Containing Monooxygenase 5Fmo 5Baeyer-Villiger Monooxygenase 1Hbvmo1Dimethylaniline Monooxygenase N-Oxide-Forming 5Dimethylaniline Oxidase 5Nadph Oxidase |
| Database Links | |
| Cellular Localisation | Microsome MembraneEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 5 antibodyAnti-Fmo 5 antibodyAnti-Baeyer-Villiger Monooxygenase 1 antibodyAnti-Hbvmo1 antibodyAnti-Dimethylaniline Monooxygenase N-Oxide-Forming 5 antibodyAnti-Dimethylaniline Oxidase 5 antibodyAnti-Nadph Oxidase antibodyAnti-FMO5 antibody |
Information sourced from Uniprot.org