Anti-FMO3 antibody [R02-1S4] (STJA0037402)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthesized peptide derived from human FMO3
General Information
| Short Description | Rabbit monoclonal anti-FMO3 for use in WB, IHC-P, ICC and IF in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ICC/IF |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R02-1S4 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100IF 1:50-1:200 |
| Formulation | Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | FMO3 |
| Gene ID | 2328 |
| Uniprot ID | FMO3_HUMAN |
| Immunogen | A synthesized peptide derived from human FMO3 |
Additional Info
| Tissue Specificity | Liver. |
| Function | Essential hepatic enzyme that catalyzes the oxygenation of a wide variety of nitrogen- and sulfur-containing compounds including drugs as well as dietary compounds. Plays an important role in the metabolism of trimethylamine (TMA), via the production of trimethylamine N-oxide (TMAO) metabolite. TMA is generated by the action of gut microbiota using dietary precursors such as choline, choline containing compounds, betaine or L-carnitine. By regulating TMAO concentration, FMO3 directly impacts both platelet responsiveness and rate of thrombus formation. |
| Protein Name | Flavin-Containing Monooxygenase 3 Dimethylaniline Monooxygenase N-Oxide-Forming 3Dimethylaniline Oxidase 3Fmo IiFmo Form 2Hepatic Flavin-Containing Monooxygenase 3Fmo 3Trimethylamine Monooxygenase |
| Database Links | Reactome: R-HSA-217271Reactome: R-HSA-5579019 |
| Cellular Localisation | Microsome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 3 antibodyAnti-Dimethylaniline Monooxygenase N-Oxide-Forming 3 antibodyAnti-Dimethylaniline Oxidase 3 antibodyAnti-Fmo Ii antibodyAnti-Fmo Form 2 antibodyAnti-Hepatic Flavin-Containing Monooxygenase 3 antibodyAnti-Fmo 3 antibodyAnti-Trimethylamine Monooxygenase antibodyAnti-FMO3 antibody |
Information sourced from Uniprot.org