Anti-FMO2 antibody (STJA0009223)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FMO2
General Information
| Short Description | Rabbit polyclonal anti-Flavin-containing monooxygenase 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FMO2 |
| Gene ID | 2327 |
| Uniprot ID | FMO2_HUMAN |
| Immunogen | Synthesized peptide derived from human FMO2 |
| Specificity | This antibody detects endogenous levels of FMO2 at Human, Mouse, Rat |
Additional Info
| Function | Catalyzes the oxidative metabolism of numerous xenobiotics, including mainly therapeutic drugs and insecticides that contain a soft nucleophile, most commonly nitrogen and sulfur and participates to their bioactivation. Specifically catalyzes S-oxygenation of sulfur derived compounds such as thioureas-derived compounds, thioetherorganophosphates to their sulfenic acid. In vitro, catalyzes S-oxygenation of the second-line antitubercular drugs thiacetazone (TAZ) and ethionamide (ETA), forming a sulfinic acid and a carbodiimide via a postulated sulfenic acid intermediate. Also catalyzes S-oxygenation of the thioether-containing organophosphate insecticides, phorate and disulfoton. |
| Protein Name | Flavin-Containing Monooxygenase 2Dimethylaniline Oxidase 2Fmo 1b1Pulmonary Flavin-Containing Monooxygenase 2Fmo 2 |
| Database Links | Reactome: R-HSA-217271 |
| Cellular Localisation | Microsome MembraneSingle-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Antibody Names | Anti-Flavin-Containing Monooxygenase 2 antibodyAnti-Dimethylaniline Oxidase 2 antibodyAnti-Fmo 1b1 antibodyAnti-Pulmonary Flavin-Containing Monooxygenase 2 antibodyAnti-Fmo 2 antibodyAnti-FMO2 antibody |
Information sourced from Uniprot.org