Anti-FMNL1 antibody (STJA0007588)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FMNL1
General Information
| Short Description | Rabbit polyclonal anti-Formin-like protein 1 for use in WB in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FMNL1 |
| Gene ID | 752 |
| Uniprot ID | FMNL1_HUMAN |
| Immunogen | Synthesized peptide derived from human FMNL1 |
| Specificity | This antibody detects endogenous levels of FMNL1 at Human, Mouse |
Additional Info
| Post Translational Modifications | Myristoylation mediates membrane localization and blebbing. |
| Function | May play a role in the control of cell motility and survival of macrophages. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the cortical actin filament dynamics and cell shape. |
| Protein Name | Formin-Like Protein 1Cll-Associated Antigen Kw-13Leukocyte Formin |
| Database Links | Reactome: R-HSA-5663220Reactome: R-HSA-9013148Reactome: R-HSA-9013149 |
| Cellular Localisation | CytoplasmCell MembraneLipid-AnchorCytoplasmic VesiclePhagosomeRecruited To Actin-Rich Phagosomes During PhagocytosisTranslocates To The Plasma Membrane Upon Activation By Rac1Isoform 3: CytoplasmCell CortexCell ProjectionBlebColocalized With F-Actin In Bleb Protrusions |
| Alternative Antibody Names | Anti-Formin-Like Protein 1 antibodyAnti-Cll-Associated Antigen Kw-13 antibodyAnti-Leukocyte Formin antibodyAnti-FMNL1 antibodyAnti-C17orf1 antibodyAnti-C17orf1B antibodyAnti-FMNL antibodyAnti-FRL1 antibody |
Information sourced from Uniprot.org