| Short Description : | Rabbit polyclonal FKBP1B (1-80) antibody for use in WB, IHC-P, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/IF/ICC/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:50-1:100IF/ICC:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FKBP1B |
| Gene ID: | 2281 |
| Uniprot ID: | FKB1B_HUMAN |
| Immunogen Region: | 1-80 |
| Immunogen Sequence: | MGVEIETISPGDGRTFPKKG QTCVVHYTGMLQNGKKFDSS RDRNKPFKFRIGKQEVIKGF EEGAAQLGPLSPLPICPHPC |
| Specificity: | A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1). |
| Tissue Specificity | Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus. |
| Function | Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1bPpiase Fkbp1b12.6 Kda Fk506-Binding Protein12.6 Kda FkbpFkbp-12.6Fk506-Binding Protein 1bFkbp-1bImmunophilin Fkbp12.6RotamaseH-Fkbp-12 |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-5578775 |
| Cellular Localisation | CytoplasmSarcoplasmic Reticulum |
| Alternative Antibody Names | Anti-Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1b antibodyAnti-Ppiase Fkbp1b antibodyAnti-12.6 Kda Fk506-Binding Protein antibodyAnti-12.6 Kda Fkbp antibodyAnti-Fkbp-12.6 antibodyAnti-Fk506-Binding Protein 1b antibodyAnti-Fkbp-1b antibodyAnti-Immunophilin Fkbp12.6 antibodyAnti-Rotamase antibodyAnti-H-Fkbp-12 antibodyAnti-FKBP1B antibodyAnti-FKBP12.6 antibodyAnti-FKBP1L antibodyAnti-FKBP9 antibodyAnti-OTK4 antibody |
Information sourced from Uniprot.org
