Anti-FKBP1B antibody (1-80) (STJ111554)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FKBP1B (1-80) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000IF/ICC:1:20-1:50ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FKBP1B |
| Gene ID | 2281 |
| Uniprot ID | FKB1B_HUMAN |
| Immunogen Region | 1-80 |
| Immunogen Sequence | MGVEIETISPGDGRTFPKKG QTCVVHYTGMLQNGKKFDSS RDRNKPFKFRIGKQEVIKGF EEGAAQLGPLSPLPICPHPC |
| Specificity | A synthetic peptide corresponding to a sequence within amino acids 1-80 of human FKBP1B (NP_473374.1). |
Additional Info
| Tissue Specificity | Detected in heart muscle (at protein level). Isoform 1 and isoform 2 are ubiquitous with highest levels in brain and thymus. |
| Function | Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. |
| Protein Name | Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1bPpiase Fkbp1b12.6 Kda Fk506-Binding Protein12.6 Kda FkbpFkbp-12.6Fk506-Binding Protein 1bFkbp-1bImmunophilin Fkbp12.6RotamaseH-Fkbp-12 |
| Database Links | Reactome: R-HSA-2672351Reactome: R-HSA-5578775 |
| Cellular Localisation | CytoplasmSarcoplasmic Reticulum |
| Alternative Antibody Names | Anti-Peptidyl-Prolyl Cis-Trans Isomerase Fkbp1b antibodyAnti-Ppiase Fkbp1b antibodyAnti-12.6 Kda Fk506-Binding Protein antibodyAnti-12.6 Kda Fkbp antibodyAnti-Fkbp-12.6 antibodyAnti-Fk506-Binding Protein 1b antibodyAnti-Fkbp-1b antibodyAnti-Immunophilin Fkbp12.6 antibodyAnti-Rotamase antibodyAnti-H-Fkbp-12 antibodyAnti-FKBP1B antibodyAnti-FKBP12.6 antibodyAnti-FKBP1L antibodyAnti-FKBP9 antibodyAnti-OTK4 antibody |
Information sourced from Uniprot.org