Anti-FIS1 antibody (27-77) (STJA0006648)

SKU:
STJA0006648

Current Stock:
Host: Rabbit
Applications: WB
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-Mitochondrial fission 1 protein (27-77) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide.
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/mL
Dilution Range: WB 1:1000-2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FIS1
Gene ID: 51024
Uniprot ID: FIS1_HUMAN
Immunogen Region: 27-77
Specificity: This antibody detects endogenous levels of human FIS1
Immunogen: Synthesized peptide derived from human FIS1 AA range: 27-77
Function Involved in the fragmentation of the mitochondrial network and its perinuclear clustering. Plays a minor role in the recruitment and association of the fission mediator dynamin-related protein 1 (DNM1L) to the mitochondrial surface and mitochondrial fission. May not be essential for the assembly of functional fission complexes and the subsequent membrane scission event. Also mediates peroxisomal fission. May act when the products of fission are directed toward mitochondrial homeostasis, mitophagy, or apoptosis. Can induce cytochrome c release from the mitochondrion to the cytosol, ultimately leading to apoptosis.
Protein Name Mitochondrial Fission 1 Protein
Fis1 Homolog
Hfis1
Tetratricopeptide Repeat Protein 11
Tpr Repeat Protein 11
Database Links Reactome: R-HSA-9603798
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Membrane Protein
Peroxisome Membrane
Alternative Antibody Names Anti-Mitochondrial Fission 1 Protein antibody
Anti-Fis1 Homolog antibody
Anti-Hfis1 antibody
Anti-Tetratricopeptide Repeat Protein 11 antibody
Anti-Tpr Repeat Protein 11 antibody
Anti-FIS1 antibody
Anti-TTC11 antibody
Anti-CGI-135 antibody

Information sourced from Uniprot.org

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