| Short Description : | Rabbit polyclonal FGGY (1-250) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FGGY |
| Gene ID: | 55277 |
| Uniprot ID: | FGGY_HUMAN |
| Immunogen Region: | 1-250 |
| Immunogen Sequence: | MSGGEQKPERYYVGVDVGTG SVRAALVDQSGVLLAFADQP IKNWEPQFNHHEQSSEDIWA ACCVVTKKVVQGIDLNQIRG LGFDATCSLVVLDKQFHPLP VNQEGDSHRNVIMWLDHRAV SQVNRINETKHSVLQYVGGV MSVEMQAPKLLWLKENLREI CWDKAGHFFDLPDFLSWKAT GVTARSLCSLVCKWTYSAEK GWDDSFWKMIGLEDFVADNY SKIGNQVLPPGASLGNGLT |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human FGGY (NP_060761.3). |
| Tissue Specificity | Expressed in kidney, lung and small intestine and to a lower extent in liver and detected in cerebrospinal fluid (at protein level). |
| Function | Catalyzes ATP-dependent phosphorylation of D-ribulose at C-5 to form D-ribulose 5-phosphate. Postulated to function in a metabolite repair mechanism by preventing toxic accumulation of free D-ribulose formed by non-specific phosphatase activities. Alternatively, may play a role in regulating D-ribulose 5-phosphate recycling in the pentose phosphate pathway. Can phosphorylate ribitol with low efficiency. |
| Protein Name | Fggy Carbohydrate Kinase Domain-Containing ProteinD-Ribulokinase Fggy |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-Fggy Carbohydrate Kinase Domain-Containing Protein antibodyAnti-D-Ribulokinase Fggy antibodyAnti-FGGY antibody |
Information sourced from Uniprot.org
