Anti-FGF21 antibody (29-209) (STJ112405)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FGF21 (29-209) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FGF21 |
| Gene ID | 26291 |
| Uniprot ID | FGF21_HUMAN |
| Immunogen Region | 29-209 |
| Immunogen Sequence | HPIPDSSPLLQFGGQVRQRY LYTDDAQQTEAHLEIREDGT VGGAADQSPESLLQLKALKP GVIQILGVKTSRFLCQRPDG ALYGSLHFDPEACSFRELLL EDGYNVYQSEAHGLPLHLPG NKSPHRDPAPRGPARFLPLP GLPPALPEPPGILAPQPPDV GSSDPLSMVGPSQGRSPSYA S |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 29-209 of human FGF21 (NP_061986.1). |
Additional Info
| Function | Stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1 expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB. Regulates systemic glucose homeostasis and insulin sensitivity. |
| Protein Name | Fibroblast Growth Factor 21Fgf-21 |
| Database Links | Reactome: R-HSA-189200Reactome: R-HSA-8963889 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 21 antibodyAnti-Fgf-21 antibodyAnti-FGF21 antibodyAnti-UNQ3115 antibodyAnti-PRO10196 antibody |
Information sourced from Uniprot.org