Anti-FGF19 antibody [SAA0439] {APC} (STJA0028928)
SPECIFICATIONS
ClonalityMonoclonal
HostMouse
ConjugationAPC
IsotypeIgG2ak
General Information
| Short Description | Mouse monoclonal Fibroblast Growth Factor 19 antibody for use in ELISA and FC in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | ELISA/FC |
| Host | Mouse |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SAA0439 |
| Isotype | IgG2ak |
| Conjugation | APC |
| Concentration | 0.5 mg/mL |
| Purification | Purified |
| Formulation | PBS pH 7.4, 50% glycerol, 0.05% proclin300 |
| Storage Instruction | Store at 4°C for 12 months. Protect from light. Do not freeze. |
Target Information
| Gene Symbol | FGF19 |
| Gene ID | 9965 |
| Uniprot ID | FGF19_HUMAN |
Additional Info
| Function | Involved in the suppression of bile acid biosynthesis through down-regulation of CYP7A1 expression, following positive regulation of the JNK and ERK1/2 cascades. Stimulates glucose uptake in adipocytes. Activity requires the presence of KLB and FGFR4. |
| Protein Name | Fibroblast Growth Factor 19Fgf-19 |
| Database Links | Reactome: R-HSA-109704Reactome: R-HSA-1257604Reactome: R-HSA-1307965Reactome: R-HSA-190322Reactome: R-HSA-2219530Reactome: R-HSA-5654228Reactome: R-HSA-5654712Reactome: R-HSA-5654719Reactome: R-HSA-5654720Reactome: R-HSA-5654733Reactome: R-HSA-5673001Reactome: R-HSA-6811558 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 19 antibodyAnti-Fgf-19 antibodyAnti-FGF19 antibodyAnti-UNQ334 antibodyAnti-PRO533 antibody |
Information sourced from Uniprot.org