Anti-FGF12 antibody (180-230 aa) (STJ13101112)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide from aa region 180-230 of human FGF12 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and rat.
General Information
| Short Description | Rabbit polyclonal anti-FGF12 (180-230 aa) for use in IHC and WB in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/WB |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | IgG purified |
| Dilution Range | IHC, WB (confirmed by recombinant protein). A dilution of 1:300 to 1:2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications. |
| Formulation | Lyophilised |
| Storage Instruction | Maintain the lyophilised/reconstituted antibodies frozen at-20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, Glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles. |
Target Information
| Gene Symbol | FGF12 |
| Gene ID | 2257 |
| Uniprot ID | FGF12_HUMAN |
| Immunogen | A synthetic peptide from aa region 180-230 of human FGF12 conjugated to an immunogenic carrier protein was used as the antigen. The peptide is homologous in mouse and rat. |
| Immunogen Region | 180-230 aa |
| Specificity | Specific for FGF12. |
Additional Info
| Function | Involved in nervous system development and function. Involved in the positive regulation of voltage-gated sodium channel activity. Promotes neuronal excitability by elevating the voltage dependence of neuronal sodium channel SCN8A fast inactivation. |
| Protein Name | Fibroblast Growth Factor 12Fgf-12Fibroblast Growth Factor Homologous Factor 1Fhf-1Myocyte-Activating Factor |
| Database Links | Reactome: R-HSA-5576892 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Fibroblast Growth Factor 12 antibodyAnti-Fgf-12 antibodyAnti-Fibroblast Growth Factor Homologous Factor 1 antibodyAnti-Fhf-1 antibodyAnti-Myocyte-Activating Factor antibodyAnti-FGF12 antibodyAnti-FGF12B antibodyAnti-FHF1 antibody |
Information sourced from Uniprot.org