Anti-FGD4 antibody (99-198) (STJ111328)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FGD4 (99-198) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FGD4 |
| Gene ID | 121512 |
| Uniprot ID | FGD4_HUMAN |
| Immunogen Region | 99-198 |
| Immunogen Sequence | QMECEEEKAATLSSDTSIQA SEPLLDTHIVNGERDETATA PASPTTDSCDGNASDSSYRT PGIGPVLPLEERGAETETKV QERENGESPLELEQLDQHHE |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 99-198 of human FGD4 (NP_640334.2). |
Additional Info
| Tissue Specificity | Expressed in different tissues, including brain, cerebellum, peripheral nerve, skeletal muscle, heart, uterus, placenta and testis. |
| Function | Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Plays a role in regulating the actin cytoskeleton and cell shape. Activates MAPK8. |
| Protein Name | Fyve - Rhogef And Ph Domain-Containing Protein 4Actin Filament-Binding Protein FrabinFgd1-Related F-Actin-Binding ProteinZinc Finger Fyve Domain-Containing Protein 6 |
| Database Links | Reactome: R-HSA-193648Reactome: R-HSA-416482Reactome: R-HSA-9013148 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionFilopodiumConcentrated In Filopodia And Poorly Detected At LamellipodiaBinds Along The Sides Of Actin Fibers |
| Alternative Antibody Names | Anti-Fyve - Rhogef And Ph Domain-Containing Protein 4 antibodyAnti-Actin Filament-Binding Protein Frabin antibodyAnti-Fgd1-Related F-Actin-Binding Protein antibodyAnti-Zinc Finger Fyve Domain-Containing Protein 6 antibodyAnti-FGD4 antibodyAnti-FRABP antibodyAnti-ZFYVE6 antibody |
Information sourced from Uniprot.org