Anti-Ferritin Heavy Chain antibody (STJA0037539)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenPeptide
General Information
| Short Description | Rabbit monoclonal anti-Ferritin Heavy Chain for use in WB and IHC-P in Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purified |
| Dilution Range | WB-1:500-1:1000IHC-1:100-1:200 |
| Formulation | Liquid in 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40%Glycerol, 0.01% sodium azide and 0.05% BSA. |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | Fth1 |
| Gene ID | 14319 |
| Uniprot ID | FRIH_MOUSE |
| Immunogen | Peptide |
Additional Info
| Function | Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. Also plays a role in delivery of iron to cells. Mediates iron uptake in capsule cells of the developing kidney. Degraded to release iron upon autophagy activation by nutrient starvation. |
| Protein Name | Ferritin Heavy ChainFerritin H Subunit Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed |
| Database Links | Reactome: R-MMU-432722Reactome: -MMU-6798695Reactome: -MMU-917937 |
| Cellular Localisation | CytoplasmCytoplasmic VesicleAutophagosomeAutolysosome |
| Alternative Antibody Names | Anti-Ferritin Heavy Chain antibodyAnti-Ferritin H Subunit Cleaved Into - Ferritin Heavy Chain - N-Terminally Processed antibodyAnti-Fth1 antibodyAnti-Fth antibody |
Information sourced from Uniprot.org