Anti-Ferredoxin Reductase antibody [SRM15012] (STJ11109742)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenRecombinant protein (or fragment).This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit monoclonal Ferredoxin Reductase antibody for use in WB, IF, ICC, IF-P, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/IF-P/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | SRM15012 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:5000-1:30000IF/ICC, 1:100-1:200IF-P, 1:100-1:200IHC-P, 1:500-1:2000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FDXR |
| Gene ID | 2232 |
| Uniprot ID | ADRO_HUMAN |
| Immunogen | Recombinant protein (or fragment).This information is considered to be commercially sensitive. |
Additional Info
| Function | Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitamin D3-24 hydroxylation in the kidney, and sterol C-27 hydroxylation in the liver. Also acts as a ferredoxin--NADP(+) reductase essential for coenzyme Q biosynthesis: together with FDX2, transfers the electrons required for the hydroxylation reaction performed by COQ6. |
| Protein Name | Nadph -Adrenodoxin Oxidoreductase - MitochondrialArAdrenodoxin ReductaseFerredoxin--Nadp(+ ReductaseFerredoxin Reductase |
| Database Links | Reactome: R-HSA-196108Reactome: R-HSA-211976Reactome: R-HSA-2395516Reactome: R-HSA-5579026 |
| Cellular Localisation | MitochondrionMitochondrion Inner MembranePeripheral Membrane Protein |
| Alternative Antibody Names | Anti-Nadph -Adrenodoxin Oxidoreductase - Mitochondrial antibodyAnti-Ar antibodyAnti-Adrenodoxin Reductase antibodyAnti-Ferredoxin--Nadp(+ Reductase antibodyAnti-Ferredoxin Reductase antibodyAnti-FDXR antibodyAnti-ADXR antibody |
Information sourced from Uniprot.org