Anti-FERMT3 antibody (52-102 aa) (STJ192926)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein at the amino acid range 52-102
General Information
| Short Description | Rabbit polyclonal anti-Fermitin family homolog 3 (52-102 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FERMT3 |
| Gene ID | 83706 |
| Uniprot ID | URP2_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein at the amino acid range 52-102 |
| Immunogen Region | 52-102 aa |
| Specificity | URP2 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Plays a central role in cell adhesion in hematopoietic cells. Acts by activating the integrin beta-1-3 (ITGB1, ITGB2 and ITGB3). Required for integrin-mediated platelet adhesion and leukocyte adhesion to endothelial cells. Required for activation of integrin beta-2 (ITGB2) in polymorphonuclear granulocytes (PMNs). Isoform 2 may act as a repressor of NF-kappa-B and apoptosis. |
| Protein Name | Fermitin Family Homolog 3Kindlin-3Mig2-Like ProteinUnc-112-Related Protein 2 |
| Database Links | Reactome: R-HSA-114608 |
| Cellular Localisation | Cell ProjectionPodosomePresent In The F-Actin Surrounding Ring Structure Of PodosomesWhich Are Specialized Adhesion Structures Of Hematopoietic Cells |
| Alternative Antibody Names | Anti-Fermitin Family Homolog 3 antibodyAnti-Kindlin-3 antibodyAnti-Mig2-Like Protein antibodyAnti-Unc-112-Related Protein 2 antibodyAnti-FERMT3 antibodyAnti-KIND3 antibodyAnti-MIG2B antibodyAnti-URP2 antibody |
Information sourced from Uniprot.org