Anti-FECH antibody (1-200) (STJ110716)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FECH (1-200) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IHC-P:1:50-1:100ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FECH |
| Gene ID | 2235 |
| Uniprot ID | HEMH_HUMAN |
| Immunogen Region | 1-200 |
| Immunogen Sequence | MRSLGANMAAALRAAGVLLR DPLASSSWRVCQPWRWKSGA AAAAVTTETAQHAQGAKPQV QPQKRKPKTGILMLNMGGPE TLGDVHDFLLRLFLDRDLMT LPIQNKLAPFIAKRRTPKIQ EQYRRIGGGSPIKIWTSKQG EGMVKLLDELSPNTAPHKYY IGFRYVHPLTEEAIEEMERD GLERAIAFTQYPQYSCSTTG |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human FECH (NP_000131.2). |
Additional Info
| Function | Catalyzes the ferrous insertion into protoporphyrin IX and participates in the terminal step in the heme biosynthetic pathway. |
| Protein Name | Ferrochelatase - MitochondrialHeme SynthaseProtoheme Ferro-Lyase |
| Database Links | Reactome: R-HSA-189451Reactome: R-HSA-9837999 |
| Cellular Localisation | Mitochondrion Inner MembranePeripheral Membrane ProteinMatrix Side |
| Alternative Antibody Names | Anti-Ferrochelatase - Mitochondrial antibodyAnti-Heme Synthase antibodyAnti-Protoheme Ferro-Lyase antibodyAnti-FECH antibody |
Information sourced from Uniprot.org