Anti-FDX1/ADX antibody [SRP15087] (STJ11109817)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide. This information is considered to be commercially sensitive.
General Information
| Short Description | Rabbit polyclonal FDX1/ADX antibody for use in WB, IP, IF, ICC, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IP/IF/ICC/IHC-P/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Clone ID | SRP15087 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity purification |
| Dilution Range | WB, 1:1000-1:9000IP, 0.5 Mu g-4 Mu g antibody for 200 Mu g-600 Mu g extracts of whole cellsIF/ICC, 1:100-1:300IHC-P, 1:500-1:2000ELISA, Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on yo |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | Fdx1 |
| Gene ID | 14148 |
| Uniprot ID | ADX_MOUSE |
| Immunogen | Synthetic peptide. This information is considered to be commercially sensitive. |
Additional Info
| Function | Essential for the synthesis of various steroid hormones, participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 that catalyzes cholesterol side-chain cleavage. Does not form a ternary complex with adrenodoxin reductase and CYP11A1 but shuttles between the two enzymes to transfer electrons. |
| Protein Name | Adrenodoxin - MitochondrialAdrenal FerredoxinFerredoxin-1 |
| Database Links | Reactome: R-MMU-1362409Reactome: -MMU-196108Reactome: -MMU-211976Reactome: -MMU-2395516Reactome: -MMU-9857492 |
| Cellular Localisation | Mitochondrion Matrix |
| Alternative Antibody Names | Anti-Adrenodoxin - Mitochondrial antibodyAnti-Adrenal Ferredoxin antibodyAnti-Ferredoxin-1 antibodyAnti-Fdx1 antibody |
Information sourced from Uniprot.org