Anti-FDPS antibody [R07-2G6] (STJA0034309)
SPECIFICATIONS
ClonalityMonoclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenA synthetic peptide of human FDPS
General Information
| Short Description | Rabbit monoclonal anti-FDPS for use in WB and IHC-P in Human and Hamster samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IHC-P |
| Host | Rabbit |
| Reactivity | Human/Hamster |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal |
| Clone ID | R07-2G6 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 0.3 mg/mL |
| Purification | Affinity Purified |
| Dilution Range | WB 1:500-1:1000IHC 1:50-1:100 |
| Formulation | 50mM Tris-Glycine (pH 7.4) , 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | FDPS |
| Gene ID | 2224 |
| Uniprot ID | FPPS_HUMAN |
| Immunogen | A synthetic peptide of human FDPS |
Additional Info
| Function | Key enzyme in isoprenoid biosynthesis which catalyzes the formation of farnesyl diphosphate (FPP), a precursor for several classes of essential metabolites including sterols, dolichols, carotenoids, and ubiquinones. FPP also serves as substrate for protein farnesylation and geranylgeranylation. Catalyzes the sequential condensation of isopentenyl pyrophosphate with the allylic pyrophosphates, dimethylallyl pyrophosphate, and then with the resultant geranylpyrophosphate to the ultimate product farnesyl pyrophosphate. |
| Protein Name | Farnesyl Pyrophosphate SynthaseFpp SynthaseFps(2e -6e-Farnesyl Diphosphate SynthaseDimethylallyltranstransferaseFarnesyl Diphosphate SynthaseGeranyltranstransferase |
| Database Links | Reactome: R-HSA-191273Reactome: R-HSA-2426168 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Farnesyl Pyrophosphate Synthase antibodyAnti-Fpp Synthase antibodyAnti-Fps antibodyAnti-(2e -6e-Farnesyl Diphosphate Synthase antibodyAnti-Dimethylallyltranstransferase antibodyAnti-Farnesyl Diphosphate Synthase antibodyAnti-Geranyltranstransferase antibodyAnti-FDPS antibodyAnti-FPS antibodyAnti-KIAA1293 antibody |
Information sourced from Uniprot.org