Anti-FCRL1 antibody (STJ192251)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-Fc receptor-like protein 1 for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FCRL1 |
| Gene ID | 115350 |
| Uniprot ID | FCRL1_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | FCRL1 Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Post Translational Modifications | Phosphorylated on tyrosines upon activation. |
| Function | Type I transmembrane surface glycoprotein preferentially expressed by B-cells that regulates BCR-mediated signaling responses. Recruits ABL1 as the intracellular effector molecule to enhance B-cell activation. Also plays a negative role by suppressing ERK activation under homeostatic and BCR-stimulated conditions in a GRB2-dependent manner. |
| Protein Name | Fc Receptor-Like Protein 1Fcr-Like Protein 1Fcrl1Fc Receptor Homolog 1Fcrh1Ifgp Family Protein 1Hifgp1Immune Receptor Translocation-Associated Protein 5Cd Antigen Cd307a |
| Database Links | |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane Protein |
| Alternative Antibody Names | Anti-Fc Receptor-Like Protein 1 antibodyAnti-Fcr-Like Protein 1 antibodyAnti-Fcrl1 antibodyAnti-Fc Receptor Homolog 1 antibodyAnti-Fcrh1 antibodyAnti-Ifgp Family Protein 1 antibodyAnti-Hifgp1 antibodyAnti-Immune Receptor Translocation-Associated Protein 5 antibodyAnti-Cd Antigen Cd307a antibodyAnti-FCRL1 antibodyAnti-FCRH1 antibodyAnti-IFGP1 antibodyAnti-IRTA5 antibody |
Information sourced from Uniprot.org