Anti-FCN2 antibody (230-290) (STJ119104)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FCN2 (230-290) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FCN2 |
| Gene ID | 2220 |
| Uniprot ID | FCN2_HUMAN |
| Immunogen Region | 230-290 |
| Immunogen Sequence | SAGDSLTFHNNQSFSTKDQD NDLNTGNCAVMFQGAWWYKN CHVSNLNGRYLRGTHGSFAN G |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 230-290 of human FCN2 (NP_004099.2). |
Additional Info
| Tissue Specificity | Expressed by the liver and secreted in plasma. |
| Function | May function in innate immunity through activation of the lectin complement pathway. Calcium-dependent and GlcNAc-binding lectin. Enhances phagocytosis of S.typhimurium by neutrophils, suggesting an opsonic effect via the collagen region. |
| Protein Name | Ficolin-237 Kda Elastin-Binding ProteinCollagen/Fibrinogen Domain-Containing Protein 2Ebp-37Ficolin-BFicolin-BetaHucolinL-FicolinSerum Lectin P35 |
| Database Links | Reactome: R-HSA-166662Reactome: R-HSA-166663Reactome: R-HSA-2855086 |
| Cellular Localisation | Secreted |
| Alternative Antibody Names | Anti-Ficolin-2 antibodyAnti-37 Kda Elastin-Binding Protein antibodyAnti-Collagen/Fibrinogen Domain-Containing Protein 2 antibodyAnti-Ebp-37 antibodyAnti-Ficolin-B antibodyAnti-Ficolin-Beta antibodyAnti-Hucolin antibodyAnti-L-Ficolin antibodyAnti-Serum Lectin P35 antibodyAnti-FCN2 antibodyAnti-FCNL antibody |
Information sourced from Uniprot.org