Anti-Fcer1a antibody [MAR-1] {PE} (STJA0002046)

SKU:
STJA0002046

Current Stock:
Host: Armenian Hamster
Applications: FC
Reactivity: Mouse
Note: FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Short Description: Armenian Hamster monoclonal antibody anti-High affinity immunoglobulin epsilon receptor subunit alpha is suitable for use in Flow Cytometry research applications.
Clonality: Monoclonal
Clone ID: MAR-1
Conjugation: PE
Isotype: IgG
Formulation: PBS with 0.05% Proclin300, 1% BSA
Concentration: 0.2 mg/mL
Storage Instruction: Recommend storing between 2-8°C and protecting from prolonged exposure to light. Do not freeze this product.
Gene Symbol: Fcer1a
Gene ID: 14125
Uniprot ID: FCERA_MOUSE
Tissue Specificity Expressed in bone marrow mast cells, as well as in the pineal gland at night.
Function High-affinity receptor for immunoglobulin epsilon/IgE. Mediates IgE effector functions in myeloid cells. Upon IgE binding and antigen/allergen cross-linking initiates signaling pathways that lead to myeloid cell activation and differentiation. On mast cells, basophils and eosinophils stimulates the secretion of vasoactive amines, lipid mediators and cytokines that contribute to inflammatory response, tissue remodeling and cytotoxicity against microbes. Triggers the immediate hypersensitivity response to allergens as a host defense mechanism against helminth parasites, pathogenic bacteria and venom toxicity. When dysregulated, it can elicit harmful life-threatening allergic and anaphylactic reactions.
Protein Name High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha
Fc-Epsilon Ri-Alpha
Fceri
Ige Fc Receptor Subunit Alpha
Database Links Reactome: R-MMU-2454202
Reactome: -MMU-2730905
Reactome: -MMU-2871796
Reactome: -MMU-2871809
Reactome: -MMU-2871837
Cellular Localisation Cell Membrane
Single-Pass Type I Membrane Protein
Alternative Antibody Names Anti-High Affinity Immunoglobulin Epsilon Receptor Subunit Alpha antibody
Anti-Fc-Epsilon Ri-Alpha antibody
Anti-Fceri antibody
Anti-Ige Fc Receptor Subunit Alpha antibody
Anti-Fcer1a antibody
Anti-Fce1a antibody

Information sourced from Uniprot.org

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