Anti-FCAR antibody (60-287) (STJ111464)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FCAR (60-287) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:200-1:1000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FCAR |
| Gene ID | 2204 |
| Uniprot ID | FCAR_HUMAN |
| Immunogen Region | 60-287 |
| Immunogen Sequence | LMIIKNSTYREIGRRLKFWN ETDPEFVIDHMDANKAGRYQ CQYRIGHYRFRYSDTLELVV TGLYGKPFLSADRGLVLMPG ENISLTCSSAHIPFDRFSLA KEGELSLPQHQSGEHPANFS LGPVDLNVSGIYRCYGWYNR SPYLWSFPSNALELVVTDSI HQDYTTQNLIRMAVAGLVLV ALLAILVENWHSHTALNKEA SADVAEPSWSQQMCQPGLTF ARTPSVCK |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 60-287 of human FCAR (NP_001991.1). |
Additional Info
| Tissue Specificity | Isoform A.1, isoform A.2 and isoform A.3 are differentially expressed between blood and mucosal myeloid cells. Isoform A.1, isoform A.2 and isoform A.3 are expressed in monocytes. Isoform A.1 and isoform A.2 are expressed in alveolar macrophages.however only one isoform is expressed at alveolar macrophages surfaces. |
| Function | Binds to the Fc region of immunoglobulins alpha. Mediates several functions including cytokine production. |
| Protein Name | Immunoglobulin Alpha Fc ReceptorIga Fc ReceptorCd Antigen Cd89 |
| Database Links | Reactome: R-HSA-6798695 |
| Cellular Localisation | Isoform A1: Cell MembraneSingle-Pass Type I Membrane Protein2: Cell Membrane3: Cell MembraneIsoform B: SecretedIsoform B-Delta-S2: Secreted |
| Alternative Antibody Names | Anti-Immunoglobulin Alpha Fc Receptor antibodyAnti-Iga Fc Receptor antibodyAnti-Cd Antigen Cd89 antibodyAnti-FCAR antibodyAnti-CD89 antibody |
Information sourced from Uniprot.org