Anti-FBXW2 antibody (102-454) (STJ118441)

SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
STJ118441
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General Information

Short DescriptionRabbit polyclonal FBXW2 (102-454) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents.
ApplicationsWB/ELISA
HostRabbit
ReactivityHuman/Mouse/Rat
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ClonalityPolyclonal
IsotypeIgG
ConjugationUnconjugated
ConcentrationLot specific
PurificationAffinity purification
Dilution RangeWB:1:500-1:2000
ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
FormulationPBS with 0.05% Proclin300, 50% Glycerol, pH 7.3.
Storage InstructionStore at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolFBXW2
Gene ID26190
Uniprot IDFBXW2_HUMAN
Immunogen Region102-454
Immunogen SequenceCKNLGWQIDDSVQDALHWKK VYLKAILRMKQLEDHEAFET SSLIGHSARVYALYYKDGLL CTGSDDLSAKLWDVSTGQCV YGIQTHTCAAVKFDEQKLVT GSFDNTVACWEWSSGARTQH FRGHTGAVFSVDYNDELDIL VSGSADFTVKVWALSAGTCL NTLTGHTEWVTKVVLQKCKV KSLLHSPGDYILLSADKYEI KIWPIGREINCKCLKTLSVS EDRSICLQPRLHFDGKYIV
SpecificityRecombinant fusion protein containing a sequence corresponding to amino acids 102-454 of human FBXW2 (NP_036296.2).

Additional Info

Function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
Protein Name F-Box/Wd Repeat-Containing Protein 2
F-Box And Wd-40 Domain-Containing Protein 2
Protein Md6
Database Links Reactome: R-HSA-390471
Reactome: R-HSA-8951664
Reactome: R-HSA-983168
Cellular Localisation
Alternative Antibody Names Anti-F-Box/Wd Repeat-Containing Protein 2 antibody
Anti-F-Box And Wd-40 Domain-Containing Protein 2 antibody
Anti-Protein Md6 antibody
Anti-FBXW2 antibody
Anti-FBW2 antibody
Anti-FWD2 antibody

Information sourced from Uniprot.org

Citations

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