Anti-FBXO46 antibody (67-117 aa) (STJ194802)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from the human FBX46 at the amino acid range 67-117
General Information
| Short Description | Rabbit polyclonal anti-F-box only protein 46 (67-117 aa) for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FBXO46 |
| Gene ID | 23403 |
| Uniprot ID | FBX46_HUMAN |
| Immunogen | Synthesized peptide derived from the human FBX46 at the amino acid range 67-117 |
| Immunogen Region | 67-117 aa |
| Specificity | This antibody detects endogenous levels of FBX46 at Human/Mouse/Rat |
Additional Info
| Function | Substrate-recognition component of the SCF(FBXO46) protein ligase complex, which mediates the ubiquitination and degradation of target proteins. In absence of stress, the SCF(FBXO46) complex catalyzes ubiquitination and degradation of MTOR-phosphorylated FBXO31. |
| Protein Name | F-Box Only Protein 46F-Box Only Protein 34-Like |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-F-Box Only Protein 46 antibodyAnti-F-Box Only Protein 34-Like antibodyAnti-FBXO46 antibodyAnti-FBX46 antibodyAnti-FBXO34L antibody |
Information sourced from Uniprot.org