| Short Description : | Rabbit polyclonal FBXO42 (468-717) antibody for use in WB, IHC-P and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications: | WB/IHC-P/ELISA |
| Host: | Rabbit |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Isotype: | IgG |
| Conjugation: | Unconjugated |
| Concentration: | Lot specific |
| Purification: | Affinity purification |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation: | PBS with 0.05% Proclin300, 50% Glycerol, pH 7.3. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FBXO42 |
| Gene ID: | 54455 |
| Uniprot ID: | FBX42_HUMAN |
| Immunogen Region: | 468-717 |
| Immunogen Sequence: | PSAPEGYDLKIGLSLAPRRG SLPDQKDLRLGSIDLNWDLK PASSSNPMDGMDNRTVGGSM RHPPEQTNGVHTPPHVASAL AGAVSPGALRRSLEAIKAMS SKGPSASAALSPPLGSSPGS PGSQSLSSGETVPIPRPGPA QGDGHSLPPIARRLGHHPPQ SLNVGKPLYQSMNCKPMQMY VLDIKDTKEKGRVKWKVFNS SSVVGPPETSLHTVVQGRGE LIIFGGLMDKKQNVKYYPK |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 468-717 of human FBXO42 (NP_061867.1). |
| Function | Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Specifically recognizes p53/TP53, promoting its ubiquitination and degradation. |
| Protein Name | F-Box Only Protein 42Just One F-Box And Kelch Domain-Containing Protein |
| Database Links | |
| Cellular Localisation | |
| Alternative Antibody Names | Anti-F-Box Only Protein 42 antibodyAnti-Just One F-Box And Kelch Domain-Containing Protein antibodyAnti-FBXO42 antibodyAnti-FBX42 antibodyAnti-JFK antibodyAnti-KIAA1332 antibody |
Information sourced from Uniprot.org
