Anti-FBXO32 antibody (206-355) (STJ28908)

Name: Anti-FBXO32 antibody (206-355) (STJ28908)
SKU: STJ28908
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

ClonalityPolyclonal

HostRabbit

ConjugationUnconjugated

IsotypeIgG

STJ28908

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Short Description	Rabbit polyclonal FBXO32 (206-355) antibody for use in WB, IF, ICC and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents.
Applications	WB/IF/ICC/ELISA
Host	Rabbit
Reactivity	Human/Mouse
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Clonality	Polyclonal
Isotype	IgG
Conjugation	Unconjugated
Concentration	Lot specific
Purification	Affinity purification
Dilution Range	WB:1:500-1:1000 IF/ICC:1:50-1:200 ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements.
Formulation	PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.

Gene Symbol	FBXO32
Gene ID	114907
Uniprot ID	FBX32_HUMAN
Immunogen Region	206-355
Immunogen Sequence	WQQQLNNIQITRPAFKGLTF TDLPLCLQLNIMQRLSDGRD LVSLGQAAPDLHVLSEDRLL WKKLCQYHFSERQIRKRLIL SDKGQLDWKKMYFKLVRCYP RKEQYGDTLQLCKHCHILSW KGTDHPCTANNPESCSVSLS PQDFINLFKF
Specificity	Recombinant fusion protein containing a sequence corresponding to amino acids 206-355 of human Fbx32/FBXO32 (NP_478136.1).

Tissue Specificity	Specifically expressed in cardiac and skeletal muscle.
Function	Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Probably recognizes and binds to phosphorylated target proteins during skeletal muscle atrophy. Recognizes TERF1.
Protein Name	F-Box Only Protein 32 Atrogin-1 Muscle Atrophy F-Box Protein Mafbx
Database Links	Reactome: R-HSA-8951664 Reactome: R-HSA-9615017 Reactome: R-HSA-983168
Cellular Localisation	Cytoplasm Nucleus Shuttles Between Cytoplasm And The Nucleus
Alternative Antibody Names	Anti-F-Box Only Protein 32 antibody Anti-Atrogin-1 antibody Anti-Muscle Atrophy F-Box Protein antibody Anti-Mafbx antibody Anti-FBXO32 antibody

Information sourced from Uniprot.org