Anti-FBP2 antibody (STJA0008138)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FBP2
General Information
| Short Description | Rabbit polyclonal anti-Fructose-1, 6-bisphosphatase isozyme 2 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FBP2 |
| Gene ID | 8789 |
| Uniprot ID | F16P2_HUMAN |
| Immunogen | Synthesized peptide derived from human FBP2 |
| Specificity | This antibody detects endogenous levels of FBP2 at Human, Mouse, Rat |
Additional Info
| Function | Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate. |
| Protein Name | Fructose-1 -6-Bisphosphatase Isozyme 2Fbpase 2D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2Muscle Fbpase |
| Database Links | Reactome: R-HSA-70263 |
| Cellular Localisation | Cell JunctionCytoplasmNucleusMyofibrilSarcomereZ LineIn Neonatal CardiomyocytesDistributed Throughout The CytosolAccumulating In The Intercalated Disks Which Occur At The Z Line Of Cardiomyocytes And Connect Adjacent CellsAnd Also Located In The NucleusDissociates From The Z Line Following An Increase In Cytosolic Ca(2+) ConcentrationIn Muscle Precursor CellsLocalizes Predominantly To The Nucleus And To A Lesser Extent To The Cytoplasm At The Proliferative PhaseWhile Mainly Localizing To The Cytoplasm At The Differentiation PhaseColocalizes With Aldoa And Alpha-Actinin On Both Sides Of The Z Line Of Skeletal MuscleDissociates Rapidly From The Z Line Following An Increase In Cytosolic Ca(2+) Concentration |
| Alternative Antibody Names | Anti-Fructose-1 -6-Bisphosphatase Isozyme 2 antibodyAnti-Fbpase 2 antibodyAnti-D-Fructose-1 -6-Bisphosphate 1-Phosphohydrolase 2 antibodyAnti-Muscle Fbpase antibodyAnti-FBP2 antibody |
Information sourced from Uniprot.org