Anti-FATE1 antibody (STJA0008976)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FATE1
General Information
| Short Description | Rabbit polyclonal anti-Fetal and adult testis-expressed transcript protein for use in WB in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20ยฐC for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FATE1 |
| Gene ID | 89885 |
| Uniprot ID | FATE1_HUMAN |
| Immunogen | Synthesized peptide derived from human FATE1 |
| Specificity | This antibody detects endogenous levels of FATE1 at Human |
Additional Info
| Function | Involved in the regulation of endoplasmic reticulum (ER)-mitochondria coupling. Negatively regulates the ER-mitochondria distance and Ca(2+) transfer from ER to mitochondria possibly implicating it in the regulation of apoptosis. May collaborate with RNF183 to restrain BIK protein levels thus regulating apoptotic signaling. |
| Protein Name | Fetal And Adult Testis-Expressed Transcript ProteinCancer/Testis Antigen 43Ct43Tumor Antigen Bj-Hcc-2 |
| Database Links | |
| Cellular Localisation | MitochondrionMitochondrion Outer MembraneEndoplasmic Reticulum MembraneSingle-Pass Membrane ProteinCytoplasmic SideLocalized To Specific Membrane Structures Termed Mitochondria-Associated Membranes (Mams) Which Connect The Endoplasmic Reticulum (Er) And The MitochondriaAlso Associated With The Outer Surface Of Mitochondria At Sites That Are Not In Close Contact With The Er |
| Alternative Antibody Names | Anti-Fetal And Adult Testis-Expressed Transcript Protein antibodyAnti-Cancer/Testis Antigen 43 antibodyAnti-Ct43 antibodyAnti-Tumor Antigen Bj-Hcc-2 antibodyAnti-FATE1 antibodyAnti-FATE antibody |
Information sourced from Uniprot.org