Anti-FANCL antibody (STJ190780)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from part of the human protein
General Information
| Short Description | Rabbit polyclonal anti-E3 ubiquitin-protein ligase FANCL for use in WB and ELISA in Human and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% Glycerol and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FANCL |
| Gene ID | 55120 |
| Uniprot ID | FANCL_HUMAN |
| Immunogen | Synthesized peptide derived from part of the human protein |
| Specificity | FANCL Polyclonal Antibody detects endogenous levels of protein. |
Additional Info
| Function | Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth. |
| Protein Name | E3 Ubiquitin-Protein Ligase FanclFanconi Anemia Group L ProteinFanconi Anemia-Associated Polypeptide Of 43 KdaFaap43Ring-Type E3 Ubiquitin Transferase Fancl |
| Database Links | Reactome: R-HSA-6783310Reactome: R-HSA-9833482 |
| Cellular Localisation | CytoplasmNucleus |
| Alternative Antibody Names | Anti-E3 Ubiquitin-Protein Ligase Fancl antibodyAnti-Fanconi Anemia Group L Protein antibodyAnti-Fanconi Anemia-Associated Polypeptide Of 43 Kda antibodyAnti-Faap43 antibodyAnti-Ring-Type E3 Ubiquitin Transferase Fancl antibodyAnti-FANCL antibodyAnti-PHF9 antibody |
Information sourced from Uniprot.org