• STJ72280 (1µg/ml) staining of Human Bone Marrow lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

Anti-FANCL antibody (Internal) (STJ72280)

SKU:
STJ72280-100

£303.50
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Host: Goat
Applications: Pep-ELISA/WB
Reactivity: Human/Mouse/Rat/Dog/Cow
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Goat polyclonal antibody anti-FANCL (Internal) is suitable for use in ELISA and Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. NA
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 0.5 mg/mL
Dilution Range: WB-1-3µg/ml
ELISA-antibody detection limit dilution 1:16000.
Storage Instruction: Store at-20°C on receipt and minimise freeze-thaw cycles.
Gene Symbol: FANCL
Gene ID: 55120
Uniprot ID: FANCL_HUMAN
Immunogen Region: Internal
Accession Number: NP_001108108.1; NP_060532.2
Specificity: This antibody is expected to recognize both isoforms (NP_001108108.1; NP_060532.2).
Immunogen Sequence: QNLKDVLEIDFP
Function Ubiquitin ligase protein that mediates monoubiquitination of FANCD2 in the presence of UBE2T, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.
Protein Name E3 Ubiquitin-Protein Ligase Fancl
Fanconi Anemia Group L Protein
Fanconi Anemia-Associated Polypeptide Of 43 Kda
Faap43
Ring-Type E3 Ubiquitin Transferase Fancl
Database Links Reactome: R-HSA-6783310
Cellular Localisation Cytoplasm
Nucleus
Alternative Antibody Names Anti-E3 Ubiquitin-Protein Ligase Fancl antibody
Anti-Fanconi Anemia Group L Protein antibody
Anti-Fanconi Anemia-Associated Polypeptide Of 43 Kda antibody
Anti-Faap43 antibody
Anti-Ring-Type E3 Ubiquitin Transferase Fancl antibody
Anti-FANCL antibody
Anti-PHF9 antibody

Information sourced from Uniprot.org

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