| Host: | Rabbit |
| Applications: | WB/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAM83A |
| Gene ID: | 84985 |
| Uniprot ID: | FA83A_HUMAN |
| Immunogen Region: | 1-160 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human FAM83A (NP_116288.2). |
| Immunogen Sequence: | MSRSRHLGKIRKRLEDVKSQ WVRPARADFSDNESARLATD ALLDGGSEAYWRVLSQEGEV DFLSSVEAQYIQAQAREPPC PPDTLGGAEAGPKGLDSSSL QSGTYFPVASEGSEPALLHS WASAEKPYLKEKSSATVYFQ TVKHNNIRDLVRRCITRTSQ |
| Post Translational Modifications | Phosphorylated upon EGFR activation. |
| Function | Probable proto-oncogene that functions in the epidermal growth factor receptor/EGFR signaling pathway. Activates both RAS/MAPK and PI3K/AKT/TOR signaling cascades downstream of EGFR. Required for the RAS/MAPK signaling cascade activation upon EGFR stimulation, it also activates both signaling cascades independently of EGFR activation. |
| Protein Name | Protein Fam83aTumor Antigen Bj-Tsa-9Tumor-Specific Gene Expressed In Prostate Protein |
| Database Links | Reactome: R-HSA-177929 |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Protein Fam83a antibodyAnti-Tumor Antigen Bj-Tsa-9 antibodyAnti-Tumor-Specific Gene Expressed In Prostate Protein antibodyAnti-FAM83A antibodyAnti-TSGP antibody |
Information sourced from Uniprot.org
![Western blot analysis of lysates from wild type (WT) and TXLNA knockout (KO) HeLa cells, using [KO Validated] TXLNA Rabbit polyclonal antibody (STJ11100765) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89702/358186/STJ11100765_1__45157.1713122500.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and TXLNA knockout (KO) HeLa cells, using [KO Validated] TXLNA Rabbit polyclonal antibody (STJ11100765) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 1s.")
![Western blot analysis of lysates from wild type (WT) and SLC25A23 knockout (KO) 293T cells, using [KO Validated] SLC25A23 Rabbit polyclonal antibody (STJ11100753) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.](https://cdn11.bigcommerce.com/s-zso2xnchw9/images/stencil/600x533/products/89691/358178/STJ11100753_1__66482.1713122487.jpg?c=1 "Western blot analysis of lysates from wild type (WT) and SLC25A23 knockout (KO) 293T cells, using [KO Validated] SLC25A23 Rabbit polyclonal antibody (STJ11100753) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 5s.")
