Anti-FAM46A antibody (180-400) (STJ114638)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FAM46A (180-400) antibody for use in WB and ELISA in human and mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TENT5A |
| Gene ID | 55603 |
| Uniprot ID | TET5A_HUMAN |
| Immunogen Region | 180-400 |
| Immunogen Sequence | PLTLKEAYVQKMVKVCNDSD RWSLISLSNNSGKNVELKFV DSLRRQFEFSVDSFQIKLDS LLLFYECSENPMTETFHPTI IGESVYGDFQEAFDHLCNKI IATRNPEEIRGGGLLKYCNL LVRGFRPASDEIKTLQRYMC SRFFIDFSDIGEQQRKLESY LQNHFVGLEDRKYEYLMTLH GVVNESTVCLMGHERRQTLN LITMLAIRVLADQNVIPNVA N |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 180-400 of human FAM46A (NP_060103.2). |
Additional Info
| Tissue Specificity | Widely expressed, with preferential expression observed in the retina compared to other ocular tissues. Also expressed in osteoblasts. |
| Function | Cytoplasmic non-canonical poly(A) RNA polymerase that catalyzes the transfer of one adenosine molecule from an ATP to an mRNA poly(A) tail bearing a 3'-OH terminal group and participates in the cytoplasmic polyadenylation. Polyadenylates mRNA encoding extracellular matrix constituents and other genes crucial for bone mineralization and during osteoblast mineralization, mainly focuses on ER-targeted mRNAs. |
| Protein Name | Terminal Nucleotidyltransferase 5aHbv X-Transactivated Gene 11 ProteinHbv Xag-Transactivated Protein 11 |
| Database Links | |
| Cellular Localisation | Cytoplasm |
| Alternative Antibody Names | Anti-Terminal Nucleotidyltransferase 5a antibodyAnti-Hbv X-Transactivated Gene 11 Protein antibodyAnti-Hbv Xag-Transactivated Protein 11 antibodyAnti-TENT5A antibodyAnti-C6orf37 antibodyAnti-FAM46A antibodyAnti-XTP11 antibody |
Information sourced from Uniprot.org