• Immunofluorescence analysis of mouse pancreas cells using FAM3B antibody (STJ23622) at dilution of 1:100. Blue: DAPI for nuclear staining.
  • Immunohistochemistry analysis of paraffin-embedded human stomach using FAM3B antibody (STJ23622) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using FAM3B antibody (STJ23622) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.
  • Immunohistochemistry analysis of paraffin-embedded human colon using FAM3B antibody (STJ23622) at dilution of 1:100 (40x lens). Perform microwave antigen retrieval with 10 mM PBS buffer pH 7. 2 before commencing with immunohistochemistry staining protocol.

Anti-FAM3B antibody (30-235) (STJ23622)

SKU:
STJ23622

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Host: Rabbit
Applications: IHC/IF
Reactivity: Human/Mouse/Rat
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FAM3B (30-235) is suitable for use in Immunohistochemistry and Immunofluorescence research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: IHC-P 1:100-1:200
IF/ICC 1:100-1:200
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FAM3B
Gene ID: 54097
Uniprot ID: FAM3B_HUMAN
Immunogen Region: 30-235
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human FAM3B (NP_478066.3).
Immunogen Sequence: ELIPDAPLSSAAYSIRSIGE RPVLKAPVPKRQKCDHWTPC PSDTYAYRLLSGGGRSKYAK ICFEDNLLMGEQLGNVARGI NIAIVNYVTGNVTATRCFDM YEGDNSGPMTKFIQSAAPKS LLFMVTYDDGSTRLNNDAKN AIEALGSKEIRNMKFRSSWV FIAAKGLELPSEIQREKINH SDAKNNRYSGWPAEIQIEGC IPKERS
Tissue Specificity Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis.
Post Translational Modifications 2 N-termini have been observed in the mature protein: the first at Glu-30, resulting from signal peptide cleavage, the second at Ser-46. O-glycosylated.
Function Induces apoptosis of alpha and beta cells in a dose- and time-dependent manner.
Protein Name Protein Fam3b
Cytokine-Like Protein 2-21
Pancreatic-Derived Factor
Pander
Cellular Localisation Secreted
Present In Insulin Secretory Granules And Likely Cosecreted With Insulin
Localized In Discrete Vesicular And Perinuclear Structure
Alternative Antibody Names Anti-Protein Fam3b antibody
Anti-Cytokine-Like Protein 2-21 antibody
Anti-Pancreatic-Derived Factor antibody
Anti-Pander antibody
Anti-FAM3B antibody
Anti-C21orf11 antibody
Anti-C21orf76 antibody
Anti-PRED44 antibody
Anti-UNQ320 antibody
Anti-PRO365 antibody

Information sourced from Uniprot.org

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