| Host: | Rabbit |
| Applications: | WB/IHC-P/ELISA |
| Reactivity: | Human/Mouse/Rat |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Clonality : | Polyclonal |
| Conjugation: | Unconjugated |
| Isotype: | IgG |
| Formulation: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Purification: | Affinity purification |
| Concentration: | Lot specific |
| Dilution Range: | WB:1:500-1:2000IHC-P:1:100-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Storage Instruction: | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: | FAM20A |
| Gene ID: | 54757 |
| Uniprot ID: | FA20A_HUMAN |
| Immunogen Region: | 140-240 |
| Specificity: | Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human FAM20A (NP_060035.2). |
| Immunogen Sequence: | YREQMNLTSLDPPLQLRLEA SWVQFHLGINRHGLYSRSSP VVSKLLQDMRHFPTISADYS QDEKALLGACDCTQIVKPSG VHLKLVLRFSDFGKAMFKPM R |
| Tissue Specificity | Highly expressed in lung and liver. Intermediate levels in thymus and ovary. |
| Post Translational Modifications | N-glycosylated. |
| Function | Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals. |
| Protein Name | Pseudokinase Fam20a |
| Database Links | Reactome: R-HSA-381426Reactome: R-HSA-8957275 |
| Cellular Localisation | SecretedGolgi ApparatusEndoplasmic Reticulum |
| Alternative Antibody Names | Anti-Pseudokinase Fam20a antibodyAnti-FAM20A antibodyAnti-UNQ9388 antibodyAnti-PRO34279 antibody |
Information sourced from Uniprot.org