| Host: |
Rabbit |
| Applications: |
WB/IF |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-DNER (140-240) is suitable for use in Western Blot and Immunofluorescence research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3. |
| Purification: |
Affinity purification |
| Dilution Range: |
WB 1:200-1:2000IF/ICC 1:50-1:200 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
DNER |
| Gene ID: |
92737 |
| Uniprot ID: |
DNER_HUMAN |
| Immunogen Region: |
140-240 |
| Immunogen: |
Recombinant fusion protein containing a sequence corresponding to amino acids 140-240 of human DNER (NP_620711.3). |
| Immunogen Sequence: |
PATGWTESMAPRQLQPVPAT QEPDKILPRSQATVTLPTWQ PKTGQKVVEMKWDQVEVIPD IACGNASSNSSAGGRLVSFE VPQNTSVKIRQDATASLILL W |
| Tissue Specificity | Expressed in brain, spinal cord and adrenal gland. |
| Function | Activator of the NOTCH1 pathway. May mediate neuron-glia interaction during astrocytogenesis. |
| Protein Name | Delta And Notch-Like Epidermal Growth Factor-Related Receptor |
| Database Links | Reactome: R-HSA-2122948 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinPresent On The Membrane Of Dendrites And Cell Bodies But Excluded From Axonal MembraneAlso Found In Early Endosomes In The Somatodendritic Region |
| Alternative Antibody Names | Anti-Delta And Notch-Like Epidermal Growth Factor-Related Receptor antibodyAnti-DNER antibodyAnti-BET antibodyAnti-UNQ262 antibodyAnti-PRO299 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
