Tissue Specificity | Widely expressed. In gastric mucosa, detected in the bottom region of the foveolar epithelium (at protein level). |
Post Translational Modifications | Arg-982 is dimethylated, probably to asymmetric dimethylarginine. Phosphorylated on tyrosine by SRC family protein kinases upon oxidative stress, for instance following UV irradiation. |
Function | Component of the oxidative stress-induced survival signaling. May regulate the activation of SRC family protein kinases. May act as a scaffolding protein enabling SRC family protein kinases to phosphorylate and activate PI3-kinase. Binds IGF2 RNA and promotes the production of IGF2 protein. |
Protein Name | Constitutive Coactivator Of Ppar-Gamma-Like Protein 1Oxidative Stress-Associated Src ActivatorProtein Fam120a |
Cellular Localisation | CytoplasmCell MembranePeripheral Membrane ProteinCytoplasmic SideTranslocates From The Cytosol To Plasma Membrane After Uv Irradiation |
Alternative Antibody Names | Anti-Constitutive Coactivator Of Ppar-Gamma-Like Protein 1 antibodyAnti-Oxidative Stress-Associated Src Activator antibodyAnti-Protein Fam120a antibodyAnti-FAM120A antibodyAnti-C9orf10 antibodyAnti-KIAA0183 antibodyAnti-OSSA antibody |
Information sourced from Uniprot.org