Anti-FAHD1 antibody (STJA0009609)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human FAHD1
General Information
| Short Description | Rabbit polyclonal anti-Acylpyruvase FAHD1, mitochondrial for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FAHD1 |
| Gene ID | 81889 |
| Uniprot ID | FAHD1_HUMAN |
| Immunogen | Synthesized peptide derived from human FAHD1 |
| Specificity | This antibody detects endogenous levels of FAHD1 at Human, Mouse, Rat |
Additional Info
| Function | Tautomerase that converts enol-oxaloacetate, a strong inhibitor of succinate dehydrogenase, to the physiological keto form of oxaloacetate. It is thereby required to maximize aerobic respiration efficiency by preventing succinate dehydrogenase inhibition. Also acts as a weak oxaloacetate decarboxylase (ODx), catalyzing the decarboxylation of oxaloacetate (OAA) to pyruvate and CO(2), and as such is likely a regulatory enzyme in the TCA cycle. Also displays acylpyruvase activity, being able to hydrolyze acetylpyruvate and fumarylpyruvate in vitro. Exhibits only a weak hydrolase activity on methylacetopyruvate and acetylacetone, and no activity toward acetoacetyl-CoA. |
| Protein Name | Oxaloacetate Tautomerase Fahd1 - MitochondrialAcylpyruvase Fahd1Fumarylacetoacetate Hydrolase Domain-Containing Protein 1Fah Domain-Containing Protein 1Oxaloacetate DecarboxylaseOaa DecarboxylaseOdxYisk-Like Protein |
| Database Links | Reactome: R-HSA-70268 |
| Cellular Localisation | MitochondrionCytoplasmCytosol |
| Alternative Antibody Names | Anti-Oxaloacetate Tautomerase Fahd1 - Mitochondrial antibodyAnti-Acylpyruvase Fahd1 antibodyAnti-Fumarylacetoacetate Hydrolase Domain-Containing Protein 1 antibodyAnti-Fah Domain-Containing Protein 1 antibodyAnti-Oxaloacetate Decarboxylase antibodyAnti-Oaa Decarboxylase antibodyAnti-Odx antibodyAnti-Yisk-Like Protein antibodyAnti-FAHD1 antibodyAnti-C16orf36 antibodyAnti-YISKL antibody |
Information sourced from Uniprot.org