Anti-FACL4 antibody [R01-5G-3] (STJA0033055)

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STJA0033055
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Short Description :Mouse monoclonal anti-FACL4 for use in WB, IHC-P, ICC and IF in Human samples. Datasheet included with dilution recommendations, and related reagents.
Applications:WB/IHC-P/ICC/IF
Host:Mouse
Reactivity:Human
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Clonality :Monoclonal
Clone ID :R01-5G-3
Isotype:IgG1k
Conjugation:Unconjugated
Purification:Protein G
Dilution Range:WB 1:500-1:1000
IHC-P 1:50-1:100
ICC:IF 1:50
Formulation:Liquid in PBS, Glycerol and BSA
Storage Instruction:Store at-20°C. Avoid freeze/thaw cycles.
Gene Symbol:ACSL4
Gene ID:2182
Uniprot ID:ACSL4_HUMAN
Immunogen:Peptide
Function Catalyzes the conversion of long-chain fatty acids to their active form acyl-CoA for both synthesis of cellular lipids, and degradation via beta-oxidation. Preferentially activates arachidonate and eicosapentaenoate as substrates. Preferentially activates 8,9-EET > 14,15-EET > 5,6-EET > 11,12-EET. Modulates glucose-stimulated insulin secretion by regulating the levels of unesterified EETs. Modulates prostaglandin E2 secretion.
Protein Name Long-Chain-Fatty-Acid--Coa Ligase 4
Arachidonate--Coa Ligase
Long-Chain Acyl-Coa Synthetase 4
Lacs 4
Database Links Reactome: R-HSA-434313
Reactome: R-HSA-75876
Cellular Localisation Mitochondrion Outer Membrane
Single-Pass Type Iii Membrane Protein
Peroxisome Membrane
Microsome Membrane
Endoplasmic Reticulum Membrane
Cell Membrane
Alternative Antibody Names Anti-Long-Chain-Fatty-Acid--Coa Ligase 4 antibody
Anti-Arachidonate--Coa Ligase antibody
Anti-Long-Chain Acyl-Coa Synthetase 4 antibody
Anti-Lacs 4 antibody
Anti-ACSL4 antibody
Anti-ACS4 antibody
Anti-FACL4 antibody
Anti-LACS4 antibody

Information sourced from Uniprot.org