• Western blot analysis of lysates from 293T cells, using FABP5 Rabbit polyclonal antibody (STJ23607) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit. Exposure time: 3min.

Anti-FABP5 antibody (1-100) (STJ23607)

SKU:
STJ23607

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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-FABP5 (1-100) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.02% Sodium Azide, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:2000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: FABP5
Gene ID: 2171
Uniprot ID: FABP5_HUMAN
Immunogen Region: 1-100
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human FABP5 (NP_001435.1).
Immunogen Sequence: MATVQQLEGRWRLVDSKGFD EYMKELGVGIALRKMGAMAK PDCIITCDGKNLTIKTESTL KTTQFSCTLGEKFEETTADG RKTQTVCNFTDGALVQHQEW
Tissue Specificity Keratinocytes.highly expressed in psoriatic skin. Expressed in brain gray matter.
Function Intracellular carrier for long-chain fatty acids and related active lipids, such as endocannabinoids, that regulate the metabolism and actions of the ligands they bind. In addition to the cytosolic transport, selectively delivers specific fatty acids from the cytosol to the nucleus, wherein they activate nuclear receptors. Delivers retinoic acid to the nuclear receptor peroxisome proliferator-activated receptor delta.which promotes proliferation and survival. May also serve as a synaptic carrier of endocannabinoid at central synapses and thus controls retrograde endocannabinoid signaling. Modulates inflammation by regulating PTGES induction via NF-kappa-B activation, and prostaglandin E2 (PGE2) biosynthesis during inflammation. May be involved in keratinocyte differentiation.
Protein Name Fatty Acid-Binding Protein 5
Epidermal-Type Fatty Acid-Binding Protein
E-Fabp
Fatty Acid-Binding Protein - Epidermal
Psoriasis-Associated Fatty Acid-Binding Protein Homolog
Pa-Fabp
Database Links Reactome: R-HSA-163560
Reactome: R-HSA-5362517
Reactome: R-HSA-6798695
Cellular Localisation Cytoplasm
Nucleus
Synapse
Postsynaptic Density
Secreted
Localizes Primarily To The Cytoplasm
Upon Certain Ligand Binding
A Conformation Change Exposes A Nuclear Localization Motif And The Protein Is Transported Into Nucleus
Secreted By Astrocytes
But Not By Neurons
Alternative Antibody Names Anti-Fatty Acid-Binding Protein 5 antibody
Anti-Epidermal-Type Fatty Acid-Binding Protein antibody
Anti-E-Fabp antibody
Anti-Fatty Acid-Binding Protein - Epidermal antibody
Anti-Psoriasis-Associated Fatty Acid-Binding Protein Homolog antibody
Anti-Pa-Fabp antibody
Anti-FABP5 antibody

Information sourced from Uniprot.org

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