Anti-FAAH2 antibody (323-532) (STJ11100505)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal FAAH2 (323-532) antibody for use in WB, IF, ICC and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/IF/ICC/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000IF/ICC:1:50-1:200ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | FAAH2 |
| Gene ID | 158584 |
| Uniprot ID | FAAH2_HUMAN |
| Immunogen Region | 323-532 |
| Immunogen Sequence | DQDLIMTQKKVVVHLETILG ASVQHVKLKKMKYSFQLWIA MMSAKGHDGKEPVKFVDLLG DHGKHVSPLWELIKWCLGLS VYTIPSIGLALLEEKLRYSN EKYQKFKAVEESLRKELVDM LGDDGVFLYPSHPTVAPKHH VPLTRPFNFAYTGVFSALGL PVTQCPLGLNAKGLPLGIQV VAGPFNDHLTLAVAQYLEKT FGGWVCPGKF |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 323-532 of human FAAH2 (NP_777572.2). |
Additional Info
| Tissue Specificity | Expressed in kidney, liver, lung, prostate, heart and ovary. |
| Function | Catalyzes the hydrolysis of endogenous amidated lipids like the sleep-inducing lipid oleamide ((9Z)-octadecenamide), the endocannabinoid anandamide (N-(5Z,8Z,11Z,14Z-eicosatetraenoyl)-ethanolamine), as well as other fatty amides, to their corresponding fatty acids, thereby regulating the signaling functions of these molecules. Hydrolyzes monounsaturated substrate anandamide preferentially as compared to polyunsaturated substrates. |
| Protein Name | Fatty-Acid Amide Hydrolase 2Amidase Domain-Containing ProteinAnandamide Amidohydrolase 2Oleamide Hydrolase 2 |
| Database Links | Reactome: R-HSA-2142753 |
| Cellular Localisation | MembraneSingle-Pass Membrane ProteinLipid Droplet |
| Alternative Antibody Names | Anti-Fatty-Acid Amide Hydrolase 2 antibodyAnti-Amidase Domain-Containing Protein antibodyAnti-Anandamide Amidohydrolase 2 antibodyAnti-Oleamide Hydrolase 2 antibodyAnti-FAAH2 antibodyAnti-AMDD antibody |
Information sourced from Uniprot.org