Anti-EXOC7 antibody (STJA0007348)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthesized peptide derived from human Exo70
General Information
| Short Description | Rabbit polyclonal anti-Exocyst complex component 7 for use in WB in Human, Mouse and Rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EXOC7 |
| Gene ID | 23265 |
| Uniprot ID | EXOC7_HUMAN |
| Immunogen | Synthesized peptide derived from human Exo70 |
| Specificity | This antibody detects endogenous levels of Exo70 at Human, Mouse, Rat |
Additional Info
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development. |
| Protein Name | Exocyst Complex Component 7Exocyst Complex Component Exo70 |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-264876Reactome: R-HSA-5620916 |
| Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinMidbodyMidbody RingTranslocatesAs A Preformed Complex With Exoc3/Sec6 And Exoc4/Sec8To The Plasma Membrane In Response To Insulin Through The Activation Of ArhqColocalizes With Cntrl/Centriolin At The Midbody Ring |
| Alternative Antibody Names | Anti-Exocyst Complex Component 7 antibodyAnti-Exocyst Complex Component Exo70 antibodyAnti-EXOC7 antibodyAnti-EXO70 antibodyAnti-KIAA1067 antibody |
Information sourced from Uniprot.org