| Host: |
Rabbit |
| Applications: |
WB |
| Reactivity: |
Human/Mouse/Rat |
| Note: |
STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Short Description: |
Rabbit polyclonal antibody anti-Exocyst complex component 7 is suitable for use in Western Blot research applications. |
| Clonality: |
Polyclonal |
| Conjugation: |
Unconjugated |
| Isotype: |
IgG |
| Formulation: |
Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Purification: |
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Concentration: |
1 mg/mL |
| Dilution Range: |
WB 1:500-2000 |
| Storage Instruction: |
Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Gene Symbol: |
EXOC7 |
| Gene ID: |
23265 |
| Uniprot ID: |
EXOC7_HUMAN |
| Specificity: |
This antibody detects endogenous levels of Exo70 at Human, Mouse, Rat |
| Immunogen: |
Synthesized peptide derived from human Exo70 |
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. In adipocytes, plays a crucial role in targeting SLC2A4 vesicle to the plasma membrane in response to insulin, perhaps directing the vesicle to the precise site of fusion. It is required for neuron survival and plays an essential role in cortical development. |
| Protein Name | Exocyst Complex Component 7Exocyst Complex Component Exo70 |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-264876Reactome: R-HSA-5620916 |
| Cellular Localisation | CytoplasmCytosolCell MembranePeripheral Membrane ProteinMidbodyMidbody RingTranslocatesAs A Preformed Complex With Exoc3/Sec6 And Exoc4/Sec8To The Plasma Membrane In Response To Insulin Through The Activation Of ArhqColocalizes With Cntrl/Centriolin At The Midbody Ring |
| Alternative Antibody Names | Anti-Exocyst Complex Component 7 antibodyAnti-Exocyst Complex Component Exo70 antibodyAnti-EXOC7 antibodyAnti-EXO70 antibodyAnti-KIAA1067 antibody |
Information sourced from Uniprot.org
12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance
