Anti-EXOC3 antibody (396-745) (STJ111223)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EXOC3 (396-745) antibody for use in WB and ELISA in human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:1000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.01% Thimerosal, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EXOC3 |
| Gene ID | 11336 |
| Uniprot ID | EXOC3_HUMAN |
| Immunogen Region | 396-745 |
| Immunogen Sequence | RKALETDKKDWVKETEPEAD QDGYYQTTLPAIVFQMFEQN LQVAAQISEDLKTKVLVLCL QQMNSFLSRYKDEAQLYKEE HLRNRQHPHCYVQYMIAIIN NCQTFKESIVSLKRKYLKNE VEEGVSPSQPSMDGILDAIA KEGCSGLLEEVFLDLEQHLN ELMTKKWLLGSNAVDIICVT VEDYFNDFAKIKKPYKKRMT AEAHRRVVVEYLRAVMQKRI SFRSPEERKEGAEKMVREA |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 396-745 of human EXOC3 (NP_009208.2). |
Additional Info
| Tissue Specificity | Expressed in epididymis (at protein level). |
| Function | Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. |
| Protein Name | Exocyst Complex Component 3Exocyst Complex Component Sec6 |
| Database Links | Reactome: R-HSA-1445148Reactome: R-HSA-264876Reactome: R-HSA-5620916 |
| Cellular Localisation | CytoplasmPerinuclear RegionCell ProjectionGrowth ConeMidbodyGolgi ApparatusNeuron ProjectionPerinuclear In Undifferentiated CellsRedistributes To Growing Neurites And Growth Cones During Neuronal DifferentiationDuring MitosisEarly Recruitment To The Midbody Requires RalaBut Not RalbAnd Exoc2In Late Stages Of CytokinesisLocalization To The Midbody Is Ralb-Dependent |
| Alternative Antibody Names | Anti-Exocyst Complex Component 3 antibodyAnti-Exocyst Complex Component Sec6 antibodyAnti-EXOC3 antibodyAnti-SEC6 antibodyAnti-SEC6L1 antibody |
Information sourced from Uniprot.org