• Western blot analysis of lysates from A-431 cells, using EXOC3 Rabbit polyclonal antibody (STJ111223). Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (STJS000856) at 1:10000 dilution. Lysates/proteins: 25 Mu g per lane. Blocking buffer: 3% nonfat dry milk in TBST.

Anti-EXOC3 antibody (396-745) (STJ111223)

SKU:
STJ111223

£265.50 - £449.50
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Host: Rabbit
Applications: WB
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Rabbit polyclonal antibody anti-EXOC3 (396-745) is suitable for use in Western Blot research applications.
Clonality: Polyclonal
Conjugation: Unconjugated
Isotype: IgG
Formulation: PBS with 0.01% Thimerosal, 50% Glycerol, pH7.3.
Purification: Affinity purification
Dilution Range: WB 1:500-1:1000
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Gene Symbol: EXOC3
Gene ID: 11336
Uniprot ID: EXOC3_HUMAN
Immunogen Region: 396-745
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 396-745 of human EXOC3 (NP_009208.2).
Immunogen Sequence: RKALETDKKDWVKETEPEAD QDGYYQTTLPAIVFQMFEQN LQVAAQISEDLKTKVLVLCL QQMNSFLSRYKDEAQLYKEE HLRNRQHPHCYVQYMIAIIN NCQTFKESIVSLKRKYLKNE VEEGVSPSQPSMDGILDAIA KEGCSGLLEEVFLDLEQHLN ELMTKKWLLGSNAVDIICVT VEDYFNDFAKIKKPYKKRMT AEAHRRVVVEYLRAVMQKRI SFRSPEERKEGAEKMVREA
Tissue Specificity Expressed in epididymis (at protein level).
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Protein Name Exocyst Complex Component 3
Exocyst Complex Component Sec6
Database Links Reactome: R-HSA-1445148
Reactome: R-HSA-264876
Reactome: R-HSA-5620916
Cellular Localisation Cytoplasm
Perinuclear Region
Cell Projection
Growth Cone
Midbody
Golgi Apparatus
Neuron Projection
Perinuclear In Undifferentiated Cells
Redistributes To Growing Neurites And Growth Cones During Neuronal Differentiation
During Mitosis
Early Recruitment To The Midbody Requires Rala
But Not Ralb
And Exoc2
In Late Stages Of Cytokinesis
Localization To The Midbody Is Ralb-Dependent
Alternative Antibody Names Anti-Exocyst Complex Component 3 antibody
Anti-Exocyst Complex Component Sec6 antibody
Anti-EXOC3 antibody
Anti-SEC6 antibody
Anti-SEC6L1 antibody

Information sourced from Uniprot.org

12 months for antibodies. 6 months for ELISA Kits. Please see website T&Cs for further guidance