Anti-EVPL antibody (1784-2033) (STJ112253)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
General Information
| Short Description | Rabbit polyclonal EVPL (1784-2033) antibody for use in WB and ELISA in human, mouse and rat samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Mouse/Rat |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | Lot specific |
| Purification | Affinity purification |
| Dilution Range | WB:1:500-1:2000ELISA:Recommended starting concentration is 1 Mu g/mL. Please optimize the concentration based on your specific assay requirements. |
| Formulation | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | EVPL |
| Gene ID | 2125 |
| Uniprot ID | EVPL_HUMAN |
| Immunogen Region | 1784-2033 |
| Immunogen Sequence | TKPSSSLSIGSIISKSPLAS PAPQSTSFFSPSFSLGLGDD SFPIAGIYDTTTDNKCSIKT AVAKNMLDPITGQKLLEAQA ATGGIVDLLSRERYSVHKAM ERGLIENTSTQRLLNAQKAF TGIEDPVTKKRLSVGEAVQK GWMPRESVLPHLQVQHLTGG LIDPKRTGRIPIQQALLSGM ISEELAQLLQDESSYEKDLT DPISKERLSYKEAMGRCRKD PLSGLLLLPAALEGYRCYR |
| Specificity | Recombinant fusion protein containing a sequence corresponding to amino acids 1784-2033 of human EVPL (NP_001979.2). |
Additional Info
| Tissue Specificity | Exclusively expressed in stratified squamous epithelia. |
| Function | Component of the cornified envelope of keratinocytes. May link the cornified envelope to desmosomes and intermediate filaments. |
| Protein Name | Envoplakin210 Kda Cornified Envelope Precursor Protein210 Kda Paraneoplastic Pemphigus AntigenP210 |
| Database Links | Reactome: R-HSA-6809371 |
| Cellular Localisation | Cell JunctionDesmosomeCornified EnvelopeCytoplasmCytoskeletonColocalized With Dsp At Desmosomes And Along Intermediate Filaments |
| Alternative Antibody Names | Anti-Envoplakin antibodyAnti-210 Kda Cornified Envelope Precursor Protein antibodyAnti-210 Kda Paraneoplastic Pemphigus Antigen antibodyAnti-P210 antibodyAnti-EVPL antibody |
Information sourced from Uniprot.org