Anti-EVC2 antibody (STJA0004555)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenSynthetic peptide of human EVC2
General Information
| Short Description | Rabbit polyclonal anti-Limbin for use in IHC and ELISA in Human samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | IHC/ELISA |
| Host | Rabbit |
| Reactivity | Human |
| Note | FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | Affinity purification |
| Dilution Range | IHC 1:50-1:200 |
| Formulation | PBS with 0.05% sodium azide and 50% glycerol, PH7.4 |
| Storage Instruction | Store at-20°C for the long term, and avoid freeze-thaw cycles. |
Target Information
| Gene Symbol | EVC2 |
| Gene ID | 132884 |
| Uniprot ID | LBN_HUMAN |
| Immunogen | Synthetic peptide of human EVC2 |
Additional Info
| Tissue Specificity | Found in the heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Plays a critical role in bone formation and skeletal development. May be involved in early embryonic morphogenesis. |
| Protein Name | LimbinEllis-Van Creveld Syndrome Protein 2Evc2 |
| Database Links | Reactome: R-HSA-5632684Reactome: R-HSA-5635838 |
| Cellular Localisation | Cell MembraneSingle-Pass Type I Membrane ProteinCytoplasmCytoskeletonCilium Basal BodyCell ProjectionCiliumCilium MembraneNucleusThe Evc Complex Localizes At The Base Of Cilia In The Evc Zone Of Primary Cilia In A Efcab7-Dependent Manner |
| Alternative Antibody Names | Anti-Limbin antibodyAnti-Ellis-Van Creveld Syndrome Protein 2 antibodyAnti-Evc2 antibodyAnti-EVC2 antibodyAnti-LBN antibody |
Information sourced from Uniprot.org