Anti-ETV6 antibody (223-272 aa) (STJ95965)
SPECIFICATIONS
ClonalityPolyclonal
HostRabbit
ConjugationUnconjugated
IsotypeIgG
ImmunogenThe antiserum was produced against synthesized peptide derived from the human Tel at the amino acid range 223-272
General Information
| Short Description | Rabbit polyclonal anti-Transcription factor ETV6 (223-272 aa) for use in WB and ELISA in Human, Rat and Mouse samples. Datasheet included with dilution recommendations, and related reagents. |
| Applications | WB/ELISA |
| Host | Rabbit |
| Reactivity | Human/Rat/Mouse |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Polyclonal |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Concentration | 1 mg/mL |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Dilution Range | WB 1:500-1:2000ELISA 1:10000 |
| Formulation | Liquid in PBS containing 50% Glycerol, 0.5% BSA and 0.02% Sodium Azide. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ETV6 |
| Gene ID | 2120 |
| Uniprot ID | ETV6_HUMAN |
| Immunogen | The antiserum was produced against synthesized peptide derived from the human Tel at the amino acid range 223-272 |
| Immunogen Region | 223-272 aa |
| Specificity | TEL Polyclonal Antibody detects endogenous levels of TEL protein. |
Additional Info
| Post Translational Modifications | Phosphorylation of Ser-257 by MAPK14 (p38) inhibits ETV6 transcriptional repression. |
| Function | Transcriptional repressor.binds to the DNA sequence 5'-CCGGAAGT-3'. Plays a role in hematopoiesis and malignant transformation. |
| Protein Name | Transcription Factor Etv6Ets Translocation Variant 6Ets-Related Protein Tel1Tel |
| Database Links | Reactome: R-HSA-9673768Reactome: R-HSA-9703465 |
| Cellular Localisation | Nucleus |
| Alternative Antibody Names | Anti-Transcription Factor Etv6 antibodyAnti-Ets Translocation Variant 6 antibodyAnti-Ets-Related Protein Tel1 antibodyAnti-Tel antibodyAnti-ETV6 antibodyAnti-TEL antibodyAnti-TEL1 antibody |
Information sourced from Uniprot.org